Preheat oven to 350° F. Place Brie round on baking sheet. With a sharp knife, cut into the rind on the top of the brie about a quarter inch from the edge. Do not remove the rind. Bake 15 minutes, or until cheese is soft and melted.
While the Brie is baking, combine in a small saucepan over medium heat, honey, balsamic vinegar, 1 tbsp of butter, 4 tbsp of water, nutmeg and orange zest. Bring to a boil; reduce the heat and simmer, stirring occasionally, until foamy, about 1-2 minutes. Stir in cranberries and sauté until wilted for about 6-7 minutes, adding a little water if too dry.
In a no sticking skillet, melt the remaining butter and cook the gnocchi according to package instructions. Season with salt and pepper.
Transfer baked Brie to a serving dish, top with the skillet gnocchi and cranberries, and then serve.